An influx of water begins to flow through the facility, sweeping Dr.

Baldwin, who tells them that the virus spreading around was created by Umbrella. King's survivors escape the facility and travel into the water treatment plant, where they find Dr. Baldwin and the sample falling into the water treatment plant below. The Tyrant does indeed rebel soon after, but succeeds in killing him and sending Dr. Carter boasts being able to kill the Tyrant should it rebel, possessing a trigger to a bomb planted within its body. Carter begins work on activating Tyrant R, intent on using it to kill the Hunters to allow for escape. Baldwin arrives and obtains the sample she needs, but with the facility on lockdown due to the escaped B.O.W.s, they can not escape. Carter, from a Zombie as the experimental Hunter Rs start escaping from containment.

At the center, survivor David King saves an Umbrella researcher, Dr. Linda Baldwin, refuses to go just yet, and rushes to the Umbrella R&D Center to obtain an antiretroviral drug that could be of use in halting the spread of the t-Virus. Captain Rodriguez, a rogue USS operator, is ready to abandon Raccoon City in a Chinook carrying a stolen B.O.W.

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